Compounded dual GIP/GLP-1 therapy · Fort Worth

Compounded tirzepatide weight loss in Fort Worth.

Compounded tirzepatide is a dual GIP and GLP-1 receptor agonist preparation that supports appetite regulation, blood sugar control, and weight management. At Highland Longevity, every prescription includes clinical follow-up, and DEXA can estimate changes in fat mass and lean mass over time. We walk through costs with you at your free consultation — no surprises.

Book Free Consultation Call (214) 444-9796
  • Physician-led Medical oversight
  • In-house DEXA body composition
  • 30 min Complimentary consultation
Dr. Joshua Lindsley reviewing a tablet with a patient during a consultation at Highland Longevity in Fort Worth

What is tirzepatide?

Two receptors, one carefully supervised plan.

Tirzepatide acts at both GIP and GLP-1 receptors. Mechanism alone does not determine candidacy or predict an individual result.

Treatment suitability, dosing, adverse effects, interactions, and monitoring require individualized clinical review.

What Highland Longevity prescribes: Highland Longevity prescribes compounded tirzepatide, prepared by a state-licensed compounding pharmacy under physician supervision. Compounded tirzepatide is not FDA-approved.

Educational background: Tirzepatide as a molecule was developed by Eli Lilly and Company and is sold under the brand names Mounjaro® (for type 2 diabetes) and Zepbound® (for chronic weight management). Highland Longevity does not dispense these brand-name products. Approved-product trials do not establish the safety, effectiveness, quality, or expected outcomes of Highland's compounded formulation or predict an individual result.

Animated diagram: twice-weekly tirzepatide acts at two receptors, GIP and GLP-1, which signal the brain to reduce hunger and increase fullness. GIP GLP-1 Hunger
  1. Twice-weekly doseA small injection, twice a week.
  2. Two receptorsActs at both GIP and GLP-1 receptors; response and tolerability vary.
  3. Appetite regulationSignals the brain to reduce hunger and increase satiety.

The Highland difference

More than a prescription. A medical practice built around obesity medicine.

A prescription is only one part of care. Here’s what surrounds every compounded tirzepatide plan at Highland.

Dr. Joshua Lindsley talking with a patient across the consultation table at Highland Longevity

01

A board-certified obesity medicine physician sets the standard

Medical leadership: Dr. Joshua Lindsley, DO, DABOM, board-certified in Obesity Medicine by the American Board of Obesity Medicine. Meet your care team.

The DEXA body composition scanner inside Highland Longevity's Fort Worth clinic

02

Progress measured in our own clinic, not just on a scale

At Highland Longevity, we combine compounded tirzepatide with DEXA scans to track objective clinical markers during your care.

“Weight loss can include fat mass and lean mass. We may use DEXA estimates to reassess nutrition, resistance training, medication, and follow-up over time.”
How DEXA body scans work

  • 03

    Straight answers about compounding

    Highland discusses FDA-approved options first and limits compounding to documented patient-specific needs.

  • 04

    Nutrition built from your numbers

    Your nutrition targets are calculated from your actual RMR and DEXA results—not generic online formulas.

    Resting metabolic rate testing

  • 05

    Follow-up that fits your week

    Highland Longevity offers telehealth follow-up appointments for tirzepatide patients throughout the DFW Metroplex.

Dosing

Dosing schedule

We split doses into twice-weekly injections for better tolerability and steadier blood levels. Dosing is individualized and follows the prescribed plan.

WeeksEach injectionWeekly total
Weeks 1-41.25mg ×22.5mg/wk total
Weeks 5-82.5mg ×25mg/wk total
Weeks 9-123.75mg ×27.5mg/wk total
Weeks 13-165mg ×210mg/wk total
Weeks 17-206.25mg ×212.5mg/wk total
Week 21+7.5mg ×215mg/wk total

Tirzepatide vs. semaglutide

MetricTirzepatideSemaglutide
MechanismDual GIP + GLP-1GLP-1 only
DosingTwice weekly (split dose)Twice weekly

A mechanism-focused comparison of tirzepatide and semaglutide. Approved-product trials do not establish outcomes for Highland's compounded formulations. Read semaglutide vs. tirzepatide.

What to expect

Tirzepatide follow-up: what we monitor

Response and timing vary. Follow-up is individualized, and no amount or timeline of weight loss is guaranteed.

  1. 01

    First visit

    Complimentary 30-minute consultation

    An in-person visit with a Highland provider to talk through your goals, our services, and next steps. No pressure, and no medical treatment at this visit.

  2. 02

    Weeks 1-4

    Early Tolerability Review

    Review adverse effects, hydration, nutrition, medication use, and early response. Dosing is individualized and follows the prescribed plan.

  3. 03

    Weeks 5-8

    Response and Dose Review

    Review weight and waist trends, appetite, adverse effects, adherence, and whether any dose change is appropriate. No pace of weight loss is guaranteed.

  4. 04

    Months 3-4

    Objective Reassessment

    Reassess treatment response, adverse effects, blood pressure, and clinically indicated laboratory markers. DEXA may estimate changes in fat mass and lean mass.

  5. 05

    Months 6-9

    Longitudinal Monitoring

    Continue individualized monitoring of response, tolerability, nutrition, activity, body-composition estimates, and clinically indicated laboratory markers.

  6. 06

    Month 12+

    Maintenance & Optimization

    Long-term planning is individualized and may include medication review, nutrition, resistance training, and monitoring for weight regain. Dose changes require clinician review.

No amount or timeline of weight loss is guaranteed. Approved-product trials do not establish outcomes for Highland's compounded formulation.

Safety

Side effects, safety & who it’s for

Side effects are similar to other GLP-1 medications, and most adverse effects are gastrointestinal and improve over time.

Compounded tirzepatide is not appropriate for everyone. Your physician will evaluate your medical history, BMI, lab values, and goals to determine candidacy.

Common side effects

  • Nausea (improves after first few weeks)
  • Diarrhea or constipation
  • Decreased appetite (the intended effect)
  • Dyspepsia (indigestion)
  • Abdominal discomfort

When to call your doctor

  • Severe or persistent nausea/vomiting
  • Signs of pancreatitis (severe abdominal pain)
  • Gallbladder symptoms (right upper abdominal pain)
  • Rapid heartbeat or dizziness
  • Signs of allergic reaction

Good candidates

  • BMI of 30 or higher (obesity)
  • BMI of 27+ with weight-related conditions
  • Interested in comparing mechanisms, risks, access, and tradeoffs
  • Haven't reached goals with other GLP-1 medications
  • Committed to lifestyle changes alongside medication

Not recommended for

  • Personal or family history of medullary thyroid cancer
  • Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
  • History of pancreatitis or gallbladder disease
  • Pregnant or planning to become pregnant
  • Currently breastfeeding

Care for your situation

Tirzepatide for specific conditions

Further reading: medical weight loss at Highland · semaglutide vs. tirzepatide · the complete weight-loss guide

Questions

Tirzepatide FAQ — Fort Worth patients

Something we didn’t cover? Call (214) 444-9796 — a real person at our Fort Worth clinic will answer.

Weight-loss outcomes vary by medication, dose, duration, adherence, health conditions, and patient. Approved-product trials do not establish outcomes for Highland's compounded formulation; no amount or timeline is guaranteed.

No. Highland discusses FDA-approved options first and limits compounding to documented patient-specific needs. We do not dispense Zepbound® or Mounjaro®, which are brand-name tirzepatide products manufactured by Eli Lilly and Company. Compounded tirzepatide is prepared by a state-licensed compounding pharmacy under physician supervision. Compounded medications are not FDA-approved.

Both contain tirzepatide as the active ingredient. Zepbound is the brand-name tirzepatide product used for weight loss. Mounjaro is the brand-name tirzepatide product used for type 2 diabetes. Highland Longevity does not prescribe either product — we prescribe compounded tirzepatide, which is prepared by a state-licensed compounding pharmacy and is not FDA-approved.

Tirzepatide acts at GIP and GLP-1 receptors, while semaglutide acts at GLP-1. Choice depends on medical history, contraindications, tolerability, access, risks, and goals. Approved-product trials do not establish outcomes for Highland's compounded formulations.

It depends on your goals and medical history. Some patients start with semaglutide and switch to tirzepatide if they plateau. Others may consider tirzepatide after individualized clinical review. We'll help you decide based on your situation during your consultation.

Studies show that stopping tirzepatide typically leads to weight regain—about two-thirds of lost weight returns within a year. This is why we emphasize body composition (preserving muscle), metabolic health, and sustainable nutrition habits alongside medication.

Compounded medications are generally not covered by health insurance. Insurance coverage typically applies only to brand-name products such as Zepbound® or Mounjaro®, which Highland Longevity does not dispense. Costs are reviewed with you at your consultation, before you start treatment.

Cost depends on your dose and protocol — microdose and therapeutic-dose programs differ — and your provider reviews it with you at your complimentary 30-minute initial consultation. The therapeutic-dose program includes medication, injection supplies, physician follow-up and dose adjustments, plus DEXA tracking.

Most patients take tirzepatide for 12-18 months to reach their weight loss goals. Some continue on a lower maintenance dose long-term to prevent regain. At Highland Longevity, we work with each patient to develop a sustainable plan that may include dose tapering, nutrition coaching, and exercise programming for weight maintenance after reaching your goal.

Yes. Highland Longevity offers telehealth follow-up appointments for tirzepatide patients throughout the DFW Metroplex. Your initial evaluation is typically in person at our Fort Worth clinic (Alliance area, 4801 Golden Triangle Blvd), with ongoing monitoring, dose adjustments, and check-ins available via telehealth for your convenience.

Highland Longevity · Fort Worth, Texas

Plan your weight loss consultation in Fort Worth

Medical leadership: Dr. Joshua Lindsley, DO, DABOM, board-certified in Obesity Medicine by the American Board of Obesity Medicine. Meet your care team.

Start with a free, 30-minute, in-person consultation with a Highland provider to discuss your goals, available services and next steps. This introductory visit is separate from medical evaluation and treatment.

Book a free introductory consultation

Visit our Fort Worth clinic

4801 Golden Triangle Blvd, Suite 121
Fort Worth, TX 76244

Monday–Friday, 8 a.m.–5 p.m.
First and second Saturdays, 10 a.m.–2 p.m.; other Saturdays closed.

Get directions(214) 444-9796

Start with a conversation

Find out whether tirzepatide fits your plan.

Book a free consultation to discuss whether tirzepatide is right for you. We'll review your medical history, prior weight loss attempts, and goals to create your personalized plan.

Book Free Consultation Call (214) 444-9796
Reception area at Highland Longevity's Fort Worth clinic

Medical disclaimer. The information on this page is for educational purposes and is not medical advice. It does not establish a physician-patient relationship and is not intended to diagnose, treat, cure, or prevent any disease. All treatments at Highland Longevity are provided under the supervision of a licensed physician. Individual results vary. Please consult a qualified healthcare provider to determine whether a given therapy is appropriate for your individual health status.

Written by Highland Longevity Clinical Team · Medically reviewed by Dr. Joshua Lindsley, DO, DABOM · Reviewed February 2026

Medical references & guidelines: Jastreboff, A. M., et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. The New England Journal of Medicine. · Eli Lilly and Company. (2023). Zepbound (tirzepatide) injection Prescribing Information. · Garvey, W. T., et al. (2023). Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial. The Lancet.